HLBS Phenotypic Deviant Report
| HLB # | 219 |
| MGI Accession # | MGI:2678710 |
| Mouse Identifier | 30941 |
| Date Mouse Born | 8/14/02 |
| Sex | Female |
| Genetic Background | C57BL/6J |
| Mutagen | ENU (See ENU Treatment Protocol) |
| Phenotype Index | Blood: Thrombocytopenia |
| Phenotype Description | At 6 weeks of age, consuming chow, this animal had a platelet count of 106 x 103 cells/µl. See the baseline comparison data for C57BL/6J in the Mouse Phenome Database. |
| Other information | |
| Heritability | The heritability of the phenotype has been confirmed. |
| Chromosome | HLB219 was mapped to strain 129S1/SvImJ. Maps to an interval of approx 14 cM on Chromosome 4, between D4Mit153 and D4Mit52. |
| Inheritance | Recessive |
| Molecular Interval | 117.9 Mb (56.5 cM) Mutation identified in Mpl (thrombopoetin recptor) Ref: Chan et al. 2006 Blood 108:329a |
| Date Posted | 1/10/03 |
| Availability | Currently available for distribution as cryopreserved homozygous embryos. |
Frequently Asked Questions About Mouse Availability
Program for Genomic Applications (PGA)
Supported by the National Heart, Lung, and Blood Institute (NHLBI) (Grant # HL66611)
