HLBS Phenotypic Deviant Report

HLB # 218
MGI Accession # MGI:2678708
Mouse Identifier 32271
Date Mouse Born 9/15/02
Sex Male
Genetic Background C57BL/6J
Mutagen ENU (See ENU Treatment Protocol)
Phenotype Index Low Total and HDL Cholesterol
Phenotype Description

At 8 weeks of age, consuming chow, this animal had a 4 hour fasted plasma Total Cholesterol of 17 mg/dl and HDL Cholesterol of 15 mg/dl. See the baseline comparison data in the Mouse Phenome Database.

Histology

HLB218 - liver x 20
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HLB218 - marrow x 60
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Other information
Heritability The heritability of the phenotype has been confirmed.
Chromosome Currently in mapping to strain 129S1/SvImJ.
Inheritance Recessive
Molecular Interval 25-82 Mb; 19-44 cM
Date Posted 8/29/03
Availability Currently available for distribution. Supply of this line may be limited by low productivity.

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Program for Genomic Applications

Program for Genomic Applications (PGA)

Supported by the National Heart, Lung, and Blood Institute (NHLBI) (Grant # HL66611)