HLBS Phenotypic Deviant Report
| HLB # | 290 |
| MGI Accession # | MGI:3578736 |
| Mouse Identifier | 36352 |
| Date Mouse Born | 11/25/02 |
| Sex | Male |
| Genetic Background | C57BL/6J |
| Mutagen | ENU (See ENU Treatment Protocol) |
| Phenotype Index | Hyperglycemia |
| Phenotype Description | At 8 weeks of age, consuming chow, this animal had a 4 hour fasted plasma glucose of 516 mg/dl. See the baseline comparison data for C57BL/6J in the Mouse Phenome Database. |
| Other information | There are 2 likewise affected siblings from this pedigree. |
| Heritability | The heritability of this phenotype has been confirmed. |
| Chromosome | HLB290 was mapped to Balb/cJ. Maps to an interval of 15 cM on Chromosome 11, between D11mit71 and D11mit51. |
| Inheritance | Recessive |
| Molecular Interval | 15 cM between D11mit71 and D11mit51, including Gck (Glucokinase) which has recently been implicated in Type II diabetes. |
| Date Posted | 5/10/05 |
| Availability | Currently available for distribution. |
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Program for Genomic Applications (PGA)
Supported by the National Heart, Lung, and Blood Institute (NHLBI) (Grant # HL66611)
