HLBS EMS Report

HLB # 258
Mouse Identifier 36768 (MGI:3575165)
Date Mouse Born 12/04/02
Sex Female
Genetic Background Mixed C57BL/6J and 129/SvJae
Mutagen ES derived
Phenotype Index Coagulopathy/low Fibrinogen
Phenotype Description At 6 weeks of age, this mouse had a plasma Fibrinogen level of 67.4. See the baseline comparison data for C57BL/6J in the Mouse Phenome Database.
Other information

62 F1s; no F2s yet but stay tuned.

One likewise affected sibling, HLB257.

Heritability The heritability of the phenotype has been confirmed.
Chromosome 3
Inheritance Recessive
Molecular Interval 60-83 Mb  (26-48 cM)  Interval includes fibrinogen peptides Fga, Fgb, Fgg. Mutation not currently being pursued.
Date Posted 8/12/03   (Report updated 1.25.07)
Availability Currently available for distribution.
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Supported by the National Heart, Lung, and Blood Institute (NHLBI) (Grant # HL66611)