HLBS Phenotypic Deviant Report

HLB # 320
MGI Accession # MGI:3575147
Mouse Identifier 39126
Date Mouse Born 1/05/03
Sex Female
Genetic Background C57BL/6J
Mutagen ENU (See ENU Treatment Protocol)
Phenotype Index Hypocholesterolemia with low HDL
Phenotype Description At 8 weeks of age, consuming chow, this animal had a 4 hour fasted plasma total Cholesterol of 35 mg/dl and HDL of 26 mg/dl. See the baseline comparison data for C57BL/6J in the Mouse Phenome Database.
Other information One affected female sibling.
Heritability The heritability of the phenotype has been confirmed.
Chromosome HLB320 was mapped to strain 129S1/SvImJ. Maps to an interval of 24 cM on Chromosome 1,  between D1Mit346 and D1Mit166.
Inheritance Dominant
Molecular Interval 24 cM between D1Mit346 and D1Mit166
Date Posted 6/18/03
Availability Currently available for distribution. Supply of this line may be limited by low productivity.

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Supported by the National Heart, Lung, and Blood Institute (NHLBI) (Grant # HL66611)