HLBS Phenotypic Deviant Report
| HLB # | 368 |
| MGI Accession # | MGI:3575125 |
| Mouse Identifier | 43691 |
| Date Mouse Born | 4/7/03 |
| Sex | Male |
| Genetic Background | C57BL/6J |
| Mutagen | ENU (See ENU Treatment Protocol) |
| Phenotype Index | Leukopenia |
| Phenotype Description | At 8 weeks of age this animal had a CBC of 1.50 x 103 WBC/µl. Retesting 2 weeks later confirmed Leukopenia, with 2.51 WBC/µl. See the baseline comparison data for C57BL/6J in the Mouse Phenome Database. |
| Other information | |
| Heritability | The heritability of this phenotype has been confirmed. |
| Chromosome | HLB368 was mapped to strain C3H/HeJ. Maps to an interval of 14cM on Chromosome 3, between D3Mit221 and D3Mit224. |
| Inheritance | Recessive |
| Molecular Interval | Mutation found in Il-7 (interleukin 7). Causes non-functional protein. |
| Date Posted | 5/7/04 |
| Availability | Currently available for distribution as cryopreserved homozygous embryos. |
Frequently Asked Questions About Mouse Availability
Program for Genomic Applications (PGA)
Supported by the National Heart, Lung, and Blood Institute (NHLBI) (Grant # HL66611)
