HLBS Phenotypic Deviant Report

HLB # 385
MGI Accession # MGI:3575129
Mouse Identifier 58721
Date Mouse Born 12/13/03
Sex Female
Genetic Background C57BL/6J
Mutagen ENU (See ENU Treatment Protocol)
Phenotype Index Leukopenia
Phenotype Description At 7 weeks of age this animal had a CBC of 3.2 x 103 WBC/µl. Retesting 2 weeks later confirmed Leukopenia. See the baseline comparison data for C57BL/6J in the Mouse Phenome Database.
Other information No other likewise affected animals identified from this pedigree to date.
Heritability The heritability of the phenotype has been confirmed.
Chromosome 10
Inheritance Recessive
Molecular Interval 82-90 Mb (42-48 cM)
Date Posted 3/5/04
Availability Available for distribution as cryopreserved homozygous embryos.

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Supported by the National Heart, Lung, and Blood Institute (NHLBI) (Grant # HL66611)