HLBS Phenotypic Deviant Report

HLB # 422
MGI Accession # Pending
Mouse Identifier 68547
Date Mouse Born 5/23/04
Sex Female
Genetic Background C57BL/6J
Mutagen ENU (See ENU Treatment Protocol)
Phenotype Index Bradycardia with prolonged QT
Phenotype Description At 11 weeks of age this mouse was found to have a low heart rate with prolonged QT interval.  On retesting one week later this observation was confirmed.

First test:  HR=634; QT=47.2 ms
Second test:  HR=651; QT=45.3 ms
Other information
Heritability The heritability of the phenotype has been confirmed.
Chromosome Unknown
Inheritance Recessive
Molecular Interval Unknown
Date Posted 5/25/06
Availability Currently available for distribution.

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Supported by the National Heart, Lung, and Blood Institute (NHLBI) (Grant # HL66611)